Artificial dura materials in neurosurgical procedures:An analysis of 100 cases
10.3969/j.issn.2095-4344.2013.29.023
- VernacularTitle:人工硬脑膜材料在神经外科手术中的应用：附100例分析☆
- Author:
Pengxiang WEI
;
Danqing LI
;
Yujia ZHOU
;
Jialin LIU
;
Lei WANG
- Publication Type:Journal Article
- Keywords:
biomaterials;
biomaterial academic discussion;
dura materials;
biocompatibility;
brain injury;
swelling polytetrafluoroethylene;
chitosan;
bovine pericardium;
silk fibroin membrane;
cerebrospinal fluid leak;
adhesions
- From:
Chinese Journal of Tissue Engineering Research
2013;(29):5415-5420
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:The meningeal defect patients can be treated with artificial dural materials combined neurosurgical techniques which can protect the integrity of brain tissue. OBJECTIVE:To analyze the biocompatibility and application feasibility of various artificial dura mater materials. METHODS:The artificial dura materials were classified according to the different sources, and the biocompatible and application feasibility of various artificial dura mater materials were analyzed, as wel as the advantages and disadvantages of various materials. The anticoagulant and hemolytic properties of the materials were analyzed through recalcification test and hemolysis test. 100 patients receiving col agen membrane repair selected from Department of Neurosurgery, Dongfang Hospital of Beijing University of Chinese Medicine were observed. RESULTS AND CONCLUSION:The dural repair materials mainly include autologous material, al ograft materials, dissimilar materials, synthetic materials and natural materials. Each kind of material has its advantages and disadvantages. Meningeal defect complications include cerebrospinal fluid leakage, pseudo meninges, infection and arachnoiditis. There are many problems of artificial dural materials to be solved, and the novel biological dural materials and absorbable materials are the direction of dural material research.
