Cervical mucinous adenocarcinoma:a pathologic analysis of twenty-one cases
10.3969/j.issn.1001-7399.2009.06.003
- VernacularTitle:子宫颈黏液腺癌21例病理诊断分析
- Author:
Qi CHE
;
Xianrong ZHONG
;
Huiting ZHU
;
Li WANG
;
Yuqing QU
;
Yan NING
- Publication Type:Journal Article
- Keywords:
cervix neoplasms;
adenocarcinoma;
pathological diagnosis;
misdiagnosis;
biopsy
- From:
Chinese Journal of Clinical and Experimental Pathology
2009;(6):580-583
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To improve the early correct diagnosis and avoid misdiagnosis of cervical mucinous adenocarcinoma.Methods Twenty-one cases of cervical mucinous adenocarcinoma were reviewed and analyzed retrospectively.The expression of CEA and Ki-67 was detected in the tumor by immunohistochemical staining (LABC method).Results Of the twenty-one cases, three cases (14.3%) were missed out, in which one was missed out by TCT and the others by biopsy; four cases (19.0%) were diagnosed by biopsy as adenocarcinoma in situ with invasion not be excluded, and then further confirmed as invasive adenocarcinoma by LEEP; one case (4.8%) was diagnosed as cervicitis at first and was further detected as adenocarcinoma by LEEP; twelve cases (57.1%) were directly diagnosed as adenocarcinoma by biopsy; one case (4.8%) was diagnosed as adenocarcinoma with unknown origin, and then as cervical adenocarcinoma after hysterectomy. Immunohistochemically, ten cases were CEA positive (47.6%) and the expression of Ki-67 was increased (>20%).Conclusions Understanding of the cytologic and histologic features of adenocarcinoma in cervix might improve its early detection and correct diagnosis, so that timely treatment is guaranteed for patients.
