Determination of chemical structure of antifungal Pityrosporum orbiculare ingredient from Alpinia galanga Swartz in Vietnam
- Author:
Huynh To Quyen
- Publication Type:Journal Article
- Keywords:
Antigungal activity;
Pityrosporum orbiculare;
Alpinia galanga Swartz;
Determination;
Chemical structure
- MeSH:
Antifungal Agents;
Malassezia
- From:Pharmaceutical Journal
2005;348(4):17-21
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Greater galangal rhizomes have been used as medicinal herbs to treat pityriasis versicolor and other diseases. By using a premilinary examination from TLC and the antifungal activity against Pityrosporum orbiculare, a new component was extracted from rhizomes of Alpinia galanga Swartz in Vietnam. The chemical structure of this component was determined by GC-MS and 1H & 13C NMR. Galangal acetate was a colorless, pungent and oily liquid. It showed the antifungal activity against P. orbiculare with MIC = 0.25 ml/ml
