Therapeutic advances on juvenile dermatomyositis
10.3760/cma.j.issn.1673-4912.2013.03.005
- VernacularTitle:重症幼年皮肌炎的治疗进展
- Author:
Guangchao SUN
;
Huasong ZENG
- Publication Type:Journal Article
- Keywords:
Juvenile dermatomyositis;
Corticosteroids;
Immunosuppressive;
Biological agents
- From:
Chinese Pediatric Emergency Medicine
2013;20(3):248-252
- CountryChina
- Language:Chinese
-
Abstract:
The current management for juvenile dermatomyositis includes the initial use of corticosteroids followed by various conventional second-line treatments such as methotrexate and azathioprine.Intravenous immunoglobulin is a reasonable short-term treatment with proven benefit.Cyclosporine or tacrolimus have shown efficacy in juvenile dermatomyositis including those patients with interstitial lung disease,whereas mycophenolate mofetil is effective in both polymyositis and refractory dermatomyositis.The curative effect of biological agents needs to be further studied.
