Relationship between myeloid-derived suppressor cells and related immune cells in the process of tumor progression
10.3760/cma.j.issn.1673-4203.2013.06.014
- VernacularTitle:髓源性抑制细胞在肿瘤进展过程中与相关免疫细胞的作用
- Author:
Shengli LIN
;
Weixin NIU
- Publication Type:Journal Article
- Keywords:
Myeloid-derived suppressor cells;
T-lymphocytes;
Dendritic cell;
Nature killer cell;
Natural killer T cell;
Macrophage;
Regulate T cell
- From:
International Journal of Surgery
2013;(6):405-408
- CountryChina
- Language:Chinese
-
Abstract:
Myeloid-derived suppressor cells are a heterogeneous population of early myeloid progenitors,immature granulocytes,macrophages,and dendritic cells at different stages of differentiation.These cells have the capacity to suppress both the innate immunity response mediated by the cytotoxic natural killer cells and natural killer T cells,and the adaptive immune response mediated by CD4+ and CD8+ T cells.In addition,myeloid-derived suppressor cells have close links with macrophages,dendritic cells,regulate T cells and so on,and also play an important role in the process of tumor progression.
