Progress of antioxidant therapy in sepsis
10.3760/cma.j.issn.1673-4203.2013.06.013
- VernacularTitle:脓毒症的抗氧化治疗进展
- Author:
Tianshu PANG
;
Daren LIU
;
Liping CAO
;
Risheng QUE
- Publication Type:Journal Article
- Keywords:
Sepsis;
Ascorbic acid;
Reactive oxygen species;
Nitric oxide synthase
- From:
International Journal of Surgery
2013;(6):402-404
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is a common acute systemic infection,severe sepsis has a high rate of mortality,and its incidence rate is rising year by year.Due to the overproduction of free radicals in sepsis,microcirculation blood is drived disorder,multiple organ function can be impaired.This review describes the role of ascorbic acid in sepsis patients,which can reverse the oxidative stress injury rapidly through an eNOS-dependent mechanism,resisting platelet adhersion,preventing capillary embolism,resevering microcirculation blood flow,so as to improve patients' survival.
