Caveolin-1 with tumour
10.3760/cma.j.issn.1673-4203.2013.06.012
- VernacularTitle:小窝蛋白1与肿瘤的关系
- Author:
Hui HOU
;
Xiaoping GENG
- Publication Type:Journal Article
- Keywords:
Cav-1;
Neoplasm metastasis;
Membrane proteins;
Growth
- From:
International Journal of Surgery
2013;(6):398-401
- CountryChina
- Language:Chinese
-
Abstract:
Caveolin are a family that proteins are highly conserved and located at the mammalian plasma membrane.They include four isoforms:Cav-1,Cav-2,Cav-3 and Cav-4.Caveolin proteins are implicated in endocytosis,lipid metabolism and cellular signaling.There is recent evidence that Cav-1 expression levels in tumour have been associated with tumour growth and metastasis,stromal car-1 expression downregulated have been also associated with mutli-tumor metastasis.
