Multiplicity of prognosis of pancreatic carcinoma patients

VernacularTitle:胰腺癌预后的多因素分析
Author: Chengbin FU ; Heguang HUANG ; Yanchang CHEN ; Fengchun LU
Publication Type:Journal Article
Keywords: Pancreatic neoplasms; COX proportional hazards survival model; Prognosis; Risk factors
From: International Journal of Surgery 2013;(5):303-306
CountryChina
Language:Chinese
Abstract: Objective To explore the factors affecting the prognosis of pancreatic cancer patients,using COX risk model to carry on the statistical analysis of 154 cases of pancreatic carcinoma.Methods Retrospectively analyzed 154 pancreatic cancer cases' history date treated in April 2001-April 2008 of Fujian Medical University Union Hospital.Survival rate was caculated by Kaplan-Meier estimation while survival cruve was analysed by Log-rank test.Prognostic factors were studied by multivariate analysis with COX proportional hazards survival model.Results In this group,survival time was from 1 to 106 months and the median survival time was 8 months.Overall survival rates at 6 months,12 months,18 months,36 months were 58.4％,29.2％,16.3％ and 3.7％ respectively.Multivariate revealed that independent prognostic factors were follows:TNM tumor staging,operation mode and synthetic therapy.Conclusions The prognosis of patients with pancreatic carcinoma is determined by multiple factors.Patients of advanced TNM staging have a poorer prognosis.Radical resection and comprehensive treatment of patients prognosis is better.