Relationship between the cardiac markers in ST-segment elevation myocardial infarction and quality of life six months later
10.3760/cma.j.issn.1673-4904.2013.10.009
- VernacularTitle:ST段抬高性心肌梗死急性期心脏标记物与六个月后生存质量的关系
- Author:
Guoming LI
;
Yanhua SUN
;
Yuwei PENG
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Cardiac marker;
Quality of life;
SF-36 health survey questionnaire
- From:
Chinese Journal of Postgraduates of Medicine
2013;(10):25-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the cardiac markers in ST-segment elevation myocardial infarction (STEMI) and quality of life (QOL) six months later.Methods N-terminal pro-B-type natriuretic peptide (NT-proBNP),cardiac troponin I (cTnI),creatine kinase isoenzyme-MB (CK-MB)and myoglobin(Myo) was tested in 76 patients with STEMI on admission(0 h) and 24 h after admission.QOL six months later was evaluated by using the SF-36 health survey questionnaire.The relationship between the cardiac markers and QOL was analyzed by multivariate linear regression analysis.Results The total SF-36 scores and the scores of physical function,body pain and general health showed negative linear correlation with NT-proBNP on admission (0 h) and 24 h after admission (P ＜ 0.05).The total SF-36 scores and the scores of physical function and body pain showed negative linear correlation with cTnI on admission (0 h)and 24 h after admission (P ＜ 0.05).The total SF-36 scores and the scores of body pain showed negative linear correlation with CK-MB on 24 h after admission (P ＜ 0.05).The scores of vitality showed negative linear correlation with Myo on admission (0 h) (P ＜ 0.05).Conclusion The higher levels of NT-proBNP,cTnl and CK-MB indicate the lower QOL six months later.
