Characteristics of apolipoprotein M and its relation to cardiovascular disease
10.3760/cma.j.issn.1009-9158.2013.06.006
- VernacularTitle:载脂蛋白M与心血管疾病相关性研究进展
- Author:
Yarong HU
;
Qian WANG
- Publication Type:Journal Article
- Keywords:
Atherosclerosis;
Apolipoproteins;
Lipoproteins,HDL
- From:
Chinese Journal of Laboratory Medicine
2013;(6):502-505
- CountryChina
- Language:Chinese
-
Abstract:
Apolipoprotein M (apoM) is a novel apolipoprotein discovered in 1999 and belongs tothe lipocalin protein superfamily.The APOM gene is mainly expressed in the liver and kidney,Where it is highly regulated by transcription factors,cytokines,hormones etc.Series of studies have shown that apoM plays an important role in lipoprotein metabolism especially in high-density lipoprotein (HDL).Since the relationship between HDL and atherosclerosis (AS) has been well known,apoM is supposed to be of potential fuctional importance in AS.Here we review the progress made in understanding the characteristics of apoM and its relationship to cardiovascular disease.
