Galectin-3 is an emerging biomarker of heart failure
10.3760/cma.j.issn.1009-9158.2013.06.007
- VernacularTitle:心力衰竭的新兴标志物—半乳糖凝集素3
- Author:
Kegang JIA
- Publication Type:Journal Article
- Keywords:
Heart failure;
Galectin 3;
Biological markers
- From:
Chinese Journal of Laboratory Medicine
2013;(6):506-510
- CountryChina
- Language:Chinese
-
Abstract:
Galectin-3 (gal-3),a member of the galectin family,is directly associated with cardiac fibrosis and cardiac remodeling.Recently it has been approved by the US Food and Drug Administration as a prognostic aid in patients with heart failure (HF).Gal-3 is associated with age,kidney function and B-type natriuretic peptide (BNP).Compared with the diagnostic utility of BNP,the long-term prognosis value of gal-3 is higher than the value of diagnosis.Higher concentration of Gal-3,a marker of cardiac fibrosis,is associated with increased risk for incident CHF and mortality.
