Effects of 660nm red light on crush-induced sciatic nerve injury
10.3760/cma.j.issn.0254-1424.2013.06.002
- VernacularTitle:660 nm红光对大鼠坐骨神经钳压损伤的修复作用
- Author:
Song LI
;
Yang ZHAO
;
Xianchao LI
;
Long CHEN
;
Yuxia CHEN
;
Ling LIU
;
Nong XIAO
- Publication Type:Journal Article
- Keywords:
Red light;
Compound muscle action potentials;
Nerve conduction velocity;
Sciatic Function Index
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2013;(6):438-441
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the therapeutic effects of 660 nm red light on sciatic nerve injury in adult rats.Methods Forty-five adult,male rats were divided into a control group and treatment groups 1,2,3 and 4.Sciatic nerve injury was modeled by crushing the nerve.The treatment groups received irradiation with red light once daily for 21 consecutive days.The power density of red light and irradiation time varied among the groups.The latency and amplitude of compound muscle action potentials (CMAPs) and nerve conductive velocity were examined at different time points.The Sciatic Function Index (SFI) was used to evaluate walking function.Results After 21 days of red light therapy no statistically significant differences were observed between the control group and treatment groups 1 to 4 with regard to the latency or the amplitude of the CMAPs.There was a significant difference between the control group and treatment group 3 in terms of sciatic nerve conduction velocity.The average Sciatic Function Indexes of treatment groups 2,3 were significantly different from that of the control group.Conclusion Red light irradiation can promote recovery after sciatic nerve injury,at least in rats,thereby improving walking function.
