Antimicrobial prophylaxis in the prevention of incisional infection after tension-free inguinal hernioplasty: a meta-analysia
10.3760/cma.j.issn.1007-631X.2013.06.017
- VernacularTitle:预防性应用抗生素对腹股沟无张力疝修补术切口感染疗效的Meta分析
- Author:
Yong WANG
;
Jingjing ZHANG
;
Yan CAO
;
Yang WU
;
Yi RUAN
- Publication Type:Journal Article
- Keywords:
Hernia,inguinal;
Antibiotic prophylaxis;
Infection;
Meta-analysis
- From:
Chinese Journal of General Surgery
2013;(6):460-463
- CountryChina
- Language:Chinese
-
Abstract:
Objective We conducted a systematic review and meta-analysis of the published literature to evaluate the efficacy of prophylactic antibiotics in the prevention of incisional infection of inguinal tension-free hernioplasty.Methods Articles of randomized controlled trials about the efficacy of prophylactic antibiotics in the prevention of incisional infection in the inguinal tension-free hernioplasty published from January 1975 to October 2012 was retrieved and systematically reviewed.Results A total of 11 randomized controlled trials meeting the inclusion criteria were screened.Among the 4159 cases of patients,130 cases had wound infection,and the infection rate was 3.13%.In the prophylactic antibiotics group of 1845 cases,wound infection occurred in 45 cases; the infection rate was 1.94%.In the control group of 2314 cases,85 cases had incision infection; the infection rate was 3.67%.The preventive use of antimicrobial drugs reduced surgical site infection of inguinal tension-free hernioplasty (OR 0.55,95% CI 0.38-0.80,P =0.002).Conclusions The use of prophylactic antibiotics can effectively reduce the incisional infection in the inguinal tension-free hernioplasty.