Polycystic ovarian syndrome- metabolic aspects
- Author:
Nguyen Vu Quoc Huy
- Publication Type:Journal Article
- Keywords:
Metabolic
- MeSH:
Polycystic Ovary Syndrome, Basal Metabolism
- From:Journal of Medical Research
2005;37(4):77-80
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Polycystic ovarian syndrome (PCOS) was not considered as a simple disease at ovary but as a metabolic syndrome. The centre of this process is the disturbance of gonadotropin and metabolism of insulin/insulin-like growth factor 1 (IGF1). Some main symptoms: mentruation disorder, hyperandrogenaemia, obesity and hyperresistant to peripheral insulin with hyperinsulinaemia. For those patients have symptoms on skin, the local treatment is provided, other systemic treatments were used for those have metabolic diseases. Women with polycystic ovarian syndrome often are obesity. Metformin lose weight, regulate menstruation circle and increase significantly ovulation. Reducing androgen concentration can improve the symptom of acne and hypertrichosis. Infertile treatment, metformin can be effect in stimulating ovaries by clomiphen or FSH, increase the rate of having pregancy and reduce the rate of miscarriage in women with PCOS.
