The relationship between hypertriglyceridemic-waist phenotype and diabetic nephropathy in patients with type 2 diabetes mellitus
10.3760/cma.j.issn.1000-6699.2013.05.005
- VernacularTitle:高甘油三酯血症-腰围表型与早期2型糖尿病肾病的相关性研究
- Author:
Ling FENG
;
Wei ZHAO
;
Xiao ZHENG
;
Hong ZHANG
- Publication Type:Journal Article
- Keywords:
Triglycerides;
Waist circumference;
Diabetes mellitus,type 2;
Microalbuminuria;
Diabetic nephropathy
- From:
Chinese Journal of Endocrinology and Metabolism
2013;(5):374-376
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] According to the cutpoint of plasma triglycerides concentration ≥ 1.7 mmol/L,waist circumference ≥85 cm in men or ≥80 cm in women,459 patiens with type 2 diabetes mellitus were divided into four groups:normal waist circumference and triglycerides,normal waist circumference and hypertriglyceridemia,abdominal obesity and normal triglycerides,and hypertriglyceridemic-waist (HTWC) group.The results showed that body mass index,waist circumference,systolic blood pressure,triglycerides,microalbuminuria,and homeostasis model assessment insulin resistance index (HOMA-IR) in HTWC group were higher than those in non-HTWC groups (all P＜0.01),as well as higher diabetic nephropathy incidence (P＜0.05).Multiple logistic regression analysis revealed that HTWC was an independent risk factor of diabetic nephropathy (OR =2.070,95 ％ CI 1.195-3.586).
