Bleomycin in a Collagen Sponge and Glaucoma Filtering Surgery.
- Author:
Dong Myung KIM
1
;
Moo Hwan CHANG
;
Se Oh OH
Author Information
1. Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Antibiotics, Antineoplastic;
Bleomycin*;
Blister;
Collagen*;
Fibroblasts;
Filtering Surgery*;
Filtration;
Glaucoma*;
Longevity;
Porifera*;
Wounds and Injuries
- From:Journal of the Korean Ophthalmological Society
1988;29(6):1043-1048
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A histologic study was performed if fibroblast proliferation could be inhibited in rab bits by deli very of bleomycin(1.35mg), an antineoplastic antibiotics, in a collagen sponge implant. Results showed that fibroblast proliferation was markedly inhibited and bleb longevity was prolonged when compared to controls. And inflammatory cell infiltration was noted around filtration wound.