The investigation and related factors analysis for the depression of patients with primary Sj(o)gren's syndrome
10.3760/cma.j.issn.1007-7480.2013.06.008
- VernacularTitle:原发性干燥综合征患者抑郁症患病率调查及相关因素分析
- Author:
Min YANG
;
Rong LIU
;
Runhua ZHOU
;
Xiaoliang DAI
;
Dong GAO
;
Hanyou MO
- Publication Type:Journal Article
- Keywords:
Sj(o)gren's syndrome;
Depressive disorder;
Cross-sectional studies
- From:
Chinese Journal of Rheumatology
2013;(6):387-391
- CountryChina
- Language:Chinese
-
Abstract:
Objective To survey the prevalence and the related factors of depression in patients with primary Sj(o)gren's syndrome (pSS),and provide references for early mental intervention.Methods The depression state of 217 patients with pSS was screened with self-rating depression scale (SDS) first and then assessed by Hamilton depression scale (HAMD,17 index).The prevalence of depression was determined based on the diagnosis of psychiatrist based on the 3rd edition of Chinese classification of mental disorders (CCMD Ⅲ).The personality was evaluated by Eysenck personality questionnaire (EPQ),and the life events were questionnaired by life events scale (LES).The general condition was analyzed by self-designed questionnaire.Finally,step-wise multiple factor regression analysis was carried out to determine the risk factors that best accounted for the depression.Results The prevalence rate of depression in patients with pSS was 39.2% (85/217).There were 5 factors entered the regression equation by multifactor regression analysis.They were severe pain,concerns of doctor and nurse,known of the fact by patients,adverse life events,and neuroticism of EPQ,and the concern of doctor and nurse was negatively correlated.Conclusion More attention from clinicians should be paid to the depression of pSS.Patients with severe pain,lack of attention from doctors and nurses,known of the disease itself,adverse life events and neurotic personality traits are factors related with depression.Recognizing the risk factors early can provide guidance for early psychological intervention.