Comparative study of inflammatory pseudoneoplasm of the liver in rabbits with fatty liver and normal liver by contrast-enhanced ultrasonography
10.3760/cma.j.issn.1004-4477.2013.06.022
- VernacularTitle:超声造影评价兔脂肪肝及正常肝背景炎性假瘤血流灌注的研究
- Author:
Yanjing ZHANG
;
Liping LIU
;
Qin LU
;
Yufang ZHAO
;
Yanhong HAO
;
Kun XU
;
Cheng CAO
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Fatty liver;
Liver diseases;
Granuloma,plasma cell
- From:
Chinese Journal of Ultrasonography
2013;(6):525-529
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze hepatic inflammatory pseudoneoplasm with fatty liver and normal liver perfusion blood characteristics and quantitative parameters using real-time contrast-enhanced ultrasound (CEUS) and time intensity curve.Methods Twenty rabbits (including ten with fatty liver and ten with normal liver) with thirty-nine inflammatory pseudoneoplasm of the liver (IPL) were studied by low mechanical index CEUS with bolus injection of SonoVue via peripheral auricular vein and QontraXt quantitative analysis software.IPL contrast-enhanced ultrasound blood perfusion characteristics with two different liver background were analyzed.Results ①According to the different pathological elements,IPL showed four kinds of CEUS types:one lesion showed absent contrast enhancement pattern (type Ⅰ),nineteen lesions showed iso-enhancement pattern (type Ⅱ),six lesions showed hypo-enhancement pattern (type Ⅲ),thirteen lesions showed fast-in and fast-out pattern (type Ⅳ).②Compared with normal liver,arrival time of fatty liver was later and its peak intensity was lower.②Compared with peripheral parenchyma,arrival time of IPL was later,peak intensity was lower and its sharpness was sharper (P ＜0.05).④Between IPL lesions with two different liver background,there was no significant difference about parameters of the time-intensity curve (P ＞0.05).Conclusions Due to different pathological elements,IPL lesions have multiform perfusion patterns in CEUS.CEUS and time intensity curve could provide enough perfusion information for IPL and liver parenchyma more accurately.
