Analysis of the hemodynamic changes of transplanted liver with acute rejection using color Doppler flow imaging: a preliminary study
10.3760/cma.j.issn.1004-4477.2013.06.012
- VernacularTitle:彩色多普勒超声评价移植肝内血流动力学变化预测急性排异的初步研究
- Author:
Hong HAN
;
Wenping WANG
;
Shaohua CHEN
;
Zhengbiao JI
;
Hong DING
;
Hui ZHANG
;
Jiexian WEN
- Publication Type:Journal Article
- Keywords:
Ultrasonography,Doppler,color;
Liver transplantation;
Graft rejection;
Portal vein;
Hemodynamic phenomena
- From:Chinese Journal of Ultrasonography
2013;(6):496-499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the viability of analysis of hemodynamic changes with color Doppler flow imaging in the prediction of acute rejection in transplanted liver.Methods Sixty-eight patients enrolled in the study were categorized into three groups:transplanted liver without acute rejection [rejection activity index(RAI) 0-3,n =24],transplanted liver with mild acute rejection (RAI 4-5,n =23),transplanted liver with moderate and severe acute rejection (RAI 6-9,n =21).All the patients were confirmed by pathology.The color Doppler flow imaging were performed in all the patients within 24 hours and 1 week after biopsy.Results In transplanted liver with moderate and severe acute rejection,the peak systolic velocity of portal vein (PV-PSV) was (31.4 ± 14.1)cm/s,significantly lower than that in transplanted liver without acute rejection,which was (45.1 ± 17.7)cm/s (P ＜0.05).A week later after steroid therapy,the PV-PSV in transplanted liver with moderate and severe rejection was increased to (46.7 ± 21.8)cm/s(P ＜0.05).Patients with acute rejection were associated with the decrease of the PVPSV (P ＜0.05).Conclusions The decrease of PV-PSV may have some clinical value in evaluation the acute rejection in transplanted liver.
