Primary experience of improving effectiveness of radiorequency ablation for liver tumor by selective portal vein embolization

VernacularTitle:经皮穿刺选择性门静脉栓塞术对增强肝恶性肿瘤射频消融作用的初步研究
Author: Liyu CHEN ; Chaowen QIAN ; Junying CHEN ; Chen YANG ; Lijing WANG ; Kaiyuan SHI ; Qiuqing ZHENG
Publication Type:Journal Article
Keywords: Ultrasonography; Liver neoplasms; Portal vein; Embolization,therapeutic; Catheter ablation
From: Chinese Journal of Ultrasonography 2013;(4):329-332
CountryChina
Language:Chinese
Abstract: Objective To explore the feasibility and efficacy of the selective portal vein embolization (SPVE) before radiofrequency ablation(RFA) for liver tumor large than 3 cm.Methods 63 patients with 63 liver tumor (＞3 cm) located in single liver segment completely or mostly underwent RFA.21 patients (21 lesions) were randomly assigned to receive SPVE before ablation (SPVE + RFA group),other 42 patients were treated with RFA only (RFA group).The complications and treat results of two groups were collected and compared.Results SPVE were achieved in 20 of 21 patients,and no critical complication were happened in both group.During a observation period of median 14.2 months,local tumor progression were observed in 17 of 42 patients (40.5％) in RFA group and in 3 of 20 patients (15.0％) in SPVE+ RFA group,there were significant difference between two groups(P =0.043).Conclusions SPVE can safely and effectively improve the efficacy of RFA for the liver tumors which large than 3 cm and located in single liver segment.