Misdiagnosis analysis of 25 cases of multiple myeloma presented initially as lumbago
10.3760/cma.j.issn.1008-6315.2013.07.004
- VernacularTitle:以腰痛为首发表现的多发性骨髓瘤25例误诊分析
- Author:
Lu SUN
- Publication Type:Journal Article
- Keywords:
Multiple myeloma;
Lumbago;
Lumbar disc
- From:
Clinical Medicine of China
2013;(7):682-684
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the reason and preventive methods from misdiagnosed cases of multiple myeloma(MM) initially manifested as lumbago.Methods Medical history and clinical data of 25 MM patients in department of hematology in our hospital were retrospectively analyzed to explore the clinical characteristics,misdiagnosis and prognosis of them.Results The 25 patients with initial presentation of lumbago were most misdiagnosed as bone and joint diseases,including 6 cases of lumbar disc,7 cases of lumbar compression fractures,6 cases of osteoporosis.And 1 cases of bone tuberculosis,3 patients of rheumatoid arthritis.And there were 2 cases of bone metastases,who were later diagnosed when anemia,neutropenia,thrombocytopenic and renal dysfunction appeared.The average misdiagnosed time was 7 months with a range of 3 months to 13 months.The median survival time was (29.2 ± 5.2) months in this group of patients.Conclusion MM,with the first manifestation of lumbago,has a single clinical manifestation and is often misdiagnosed as bone and joint diseases.Specialists who are not from hematology department should raise awareness and vigilance of the disease.Laboratory examinations results should be referred to in the diagnosis.Sum up experience in order to improve the early diagnosis of this disease and to effectively improve patient's prognosis and quality of life.
