Recent correlation of severity and prognosis of B-type natriuretic peptide to no heart disease patients in ICU

VernacularTitle:B型钠尿肽与非心脏病ICU患者严重程度及近期预后的相关性研究
Author: Yongzhang RONG ; Huaxin LIN ; Jinying ZENG
Publication Type:Journal Article
Keywords: B-type natriuretic peptide; APACHE Ⅱ score; Critical Care; Prognosis
From: Clinical Medicine of China 2013;(7):718-720
CountryChina
Language:Chinese
Abstract: Objective To investigate the correlations of short-term prognosis and B-type natriuretic peptide(BNP) of no heart disease patients in ICU.Methods Sixty patients of critically ill in our ICU ward from March 2010 to March 2012 were taken scores of acute physiology and chronic health Ⅱ scoring system (APACHE Ⅱ score) and determination serum BNP level in 24 hours of admission and analysis mortality in hospital time,mechanical ventilation time and other major prognostic indicators.Results Forty-two cases were living,18 cases were dead in the 60 cases (mortality rate 30％).APACHE Ⅱ score (26.46 ± 11.6) and serum BNP concentrations(2154.26 ± 1126.49) ng/L were significantly higher in death cases than in living cases (13.45 ± 4.20) vs.(1058.16 ± 857.83) ng/L (t =6.4055,4.1190,P ＜ 0.001),mechanical ventilation time mortality rate both also increase with BNP levels (F =49.089,22.754,36.398 respectively,P ＜ 0.001).Conclusion BNP level and APACHE Ⅱ score rise of survival of critically ill patients have important prognostic significance with duration of mechanical ventilation,length of hospital stay prognostic indicators forecast.