Observation on the effect of endoscopic sinus low-temperature plasma-assisted sinus surgery combined with antifungal drug in treatment of fungal nasal-sinusitis
10.3760/cma.j.issn.1008-6706.2013.14.015
- VernacularTitle:鼻内镜低温等离子辅助下鼻窦手术联合抗真菌药物治疗真菌性鼻-鼻窦炎的疗效观察
- Author:
Zuguo MA
;
Wei HU
- Publication Type:Journal Article
- Keywords:
Otorhinolaryngologic surgical procedures;
Antifungal agents;
Sinusitis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(14):2117-2118
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical effect of surgery combined with antifungal drug in treatment of fungal nose-sinusitis.Methods The clinical data of 108 cases with fungal nose-sinusitis were retrospectively analyzed.All patients were treated with nasal endoscopic sinus surgery.According to whether the patients received antifungal drugs after low-temperature plasma-assisted surgery,the patients were divided into the treatment group and the control group.The treatment group(56 cases) was given antifungal fluconazole after low-temperature plasma-assisted endoscopic sinus surgery.52 cases in the control group were washed by 0.9％ sodium chloride solution after conventional endoscopic sinus surgery.The patients were followed up for 6 months to 2 years,the therapeutic effect and recurrence were compared between the two groups.Results 56 patients of the treatment group,49 cases were cured,7 cases improved,no recurrence.52 cases in the control group,47 cases were cured,improved in 4 cases,ineffective in 1 case,3 cases of recurrence.The recurrence rate of the treatment group was significantly lower than the control group (x2 =4.82,P ＜ 0.05).Conclusion The low-temperature plasma-assisted surgery combined with antifungal drug.in the treatment of fungal nose-sinusitis has exact efficacy,and has significant effect on the prevention and reduce the relapse rate,which worthy of clinical promotion.
