Observation on the effect of montelukast and ambroxol hydrochloride in treatment respiratory tract symptoms in children with mycoplasma pneumoniae infection
10.3760/cma.j.issn.1008-6706.2013.14.006
- VernacularTitle:孟鲁司特、氨溴特罗改善小儿肺炎支原体感染所致呼吸道症状的疗效观察
- Author:
Jie YANG
;
Huijuan SUN
;
Yu WANG
- Publication Type:Journal Article
- Keywords:
Mycoplasma pulmonis;
Respiratory tract diseases;
Montelukast;
Ambroxol hydrochloride;
Clenbuterol hydrochloride
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(14):2095-2096
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of montelukast sodium and ambroxol oral solution in treatment respiratory symptoms caused by mycoplasma infection in children.Methods 147 children who were infected by mycoplasma pneumonia with lower respiratory tracts symptom were randomly divided into A,B,C three groups:group A was control group,group B was treated by montelukast sodium,and group C was treated by montelukast sodium and ambroxol oral solution.Coughing,symptomatic relief of pant were observed in each group.Results After 7 days treatment,the total effective rate of three groups was A group 79.5%,B group 95.7%,C group 96.4%.Compared with group A,the coughing and panting time in group B and group C were significantly shorter(x2 =5.61,9.54,all P <0.05),The rate of coughing and panting complete remission in group C was higher compared with group B (x2 =5.39,P < 0.05),but there was no statistificantly significant difference in the total efficency between the two groups.Conclusion Montelukast sodium and ambroxol oral solution can effectively improve the symptoms of respiratory tract infection caused by mycoplasma pneumoniae.