Clinical significance of IgE and IL-5 in diagnosis of mycoplasma pneumoniae children with bronchial asthma

VernacularTitle:免疫球蛋白E及白细胞介素5在肺炎支原体感染合并哮喘患儿诊断中的意义
Author: Yuanda LU ; Li YU
Publication Type:Journal Article
Keywords: Mycoplasma pulmonis; Asthma; Immunoglobulin E; Interleukin-5
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(13):1975-1977
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical value of IgE and IL-5 in diagnosis of mycoplasma pneumoniae children with bronchial asthma.Methods 40 mycoplasma pneumoniae infection children complicated with bronchial asthma were chosen as the observation group,the other 40 mycoplasma pneumoniae infection children without bronchial asthma were selected as the control group.All children were admitted to hospital,the next morning fasting blood was obtained to detect IgE and IL-5 levels.Results The serum total IgE level of observation group was (335.74 ±38.84) IU/ml,the level of IL-5 was (311.86 ± 35.28) ng/L,which were significantly higher than control group (P ＜0.05).Binary Logistic regression analysis showed that,serum IgE level and IL-5 level had statistically significant difference (P ＜ 0.05).Conclusion Mycoplasma pneumoniae infection in children with bronchial asthma,the IgE and IL-5 levels increased more obviously,and the levels of serum IgE and IL-5 were important risk factors of onset of children with Mycoplasma pneumoniae infection combined bronchial asthma.