A Case of a Perivascular Epithelioid Cell Tumor Mimicking Colon Cancer.
10.4166/kjg.2012.60.6.377
- Author:
Young Whan CHO
1
;
Kyung Jo KIM
;
Byong Duk YE
;
Jeong Sik BYEON
;
Seung Jae MYUNG
;
Suk Kyun YANG
;
Jin Ho KIM
Author Information
1. Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. capsulendos@gmail.com
- Publication Type:Case Reports ; English Abstract
- Keywords:
Perivascular epithelioid cell tumor;
Colonoscopy;
Intestines
- MeSH:
Colonic Neoplasms/diagnosis;
Colonoscopy;
Female;
Gastrointestinal Hemorrhage;
Humans;
Melanoma-Specific Antigens/metabolism;
Middle Aged;
Perivascular Epithelioid Cell Neoplasms/*diagnosis/pathology/surgery;
Tomography, X-Ray Computed
- From:The Korean Journal of Gastroenterology
2012;60(6):377-381
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Perivascular epithelioid cell tumor (PEComa) is extremely rare, which originated from mesenchymal cells in the intestine, and composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. We report here on a case of PEComa in the sigmoid colon. A 62-year-old woman presented with hematochzia 10 days ago. Her abdominal computed tomography scan showed a 5 cm sized intraluminal fungating heterogeneously enhanced, high density mass, which infiltrated pericolic tissue surrounding the sigmoid colon. Colonoscopy showed a purple colored polypoid mass with lobulating contour in the sigmoid colon. She underwent laparoscopic anterior resection. On the histologic examination, the tumor consisted of polygonal epithelioid cells with sheet-like growth of nests, which looked like alveolar tissues in lung. The tumor cells were strongly positive stained with human melanoma black-45 (HMB-45). Pathologic examination was compatible with PEComa. Sixteen months after surgery, she did well without tumor recurrence after surgery. We review the literatures concerning PEComa of the intestine focusing on endoscopic findings.
