Clinical observations on the efficacy of point-injection with NGF in treatment of infantile cerebral palsy

VernacularTitle:神经生长因子穴位注射治疗小儿脑性瘫痪疗效观察
Author: Weihua CHEN ; Man HUANG ; Jiang ZHOU
Publication Type:Journal Article
Keywords: Cerebral palsy; Point-injection; Rehabilitation; Nerve growth factor
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(12):1830-1832
CountryChina
Language:Chinese
Abstract: Objective To discuss the clinical efficacy of point-injection with nerve growth factor (NGF) in treatment of infantile cerebral palsy.Methods According to the time order,50 cases with cerebral palsy were randomly divided into the treatment group(30 cases) and the control group (20 cases).Both groups were given the conventional treatment of Bobath mainly exercise therapy,homework therapy and the language therapy.In addition,the treatment group was given the treatment of point-injection with NGF.Gesell scale was used to evaluate all the patients before and after treatment.Results After treatment,the Gesell evaluation of the treatment group was higher than control group,and the difference was statistically significant (t =-2.096,-2.187,-2.048,-2.053,-2.225,all P ＜0.05).Conclusion On the basis of rehabilitation training,point-injection with NGF could improve intelligence,motor function and language in children with cerebral palsy,and the efficacy was obvious.