The clinical study of the new formula for estimating the glomerular filtration rate for adult Chinese

VernacularTitle:成年人肾小球滤过率估算新公式临床研究
Author: Xixin WU
Publication Type:Journal Article
Keywords: Glomerular filtration rate; Clearance rate of 99mTc-DTPA; Cystatin C; Creatinine; Blood urea nitrogen; Adult
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(12):1788-1790
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical application value of the new formula for estimating glomerular filtration rate(eGFR) for adult Chinese(AC-eGFR).Methods GFR from 117 patients in hospital suffering from the difference diseases was determined accurately using clearance rate of 99mTc-DTPA(Tc-GFR).The serum cystatin C,creatinine and blood urea nitrogen were determined by the biochemical apparatus.Simultaneously,GFR was calculated by the eleven formulas such as AC-eGFR,CKD-EPI formula etc..Then,the results were compared and analyzed.Results eGFR from the eleven formulas could all give expression to GFR accurately in some extent,AC-eGFR,CKDEPI-eGFR and Larsson A et al-eGFR were more accurate than others and could take place of Tc-GFR clinically.Robert TT-eGFR,Filler Get al-eGFR and Grubb Aet al-eGFR were worse than others.Conclusion AC-eGFR,CKDEPI-eGFR and Larsson A et al-eGFR were all accurate,simple,fast,safe,cheap and rational method for estimatingGFR,which should apply and popularize clinically.