Study on the correlation between the level of serum uric acid and high-sensitivity C-reactive protein with sudden cardiac death of coronary artery disease
10.3760/cma.j.issn.1008-6706.2013.11.002
- VernacularTitle:血尿酸和超敏C反应蛋白与冠心病心脏性猝死的相关性研究
- Author:
Hui ZOU
;
Xiaojie LI
;
Xin WANG
;
Shengnan CAI
- Publication Type:Journal Article
- Keywords:
Uric acid;
C-reactive protein;
Coronary artery disease;
Death,sudden,cardiac;
Prognosis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(11):1604-1605
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between the level of serum uric acid (UA) and high-sensitivity C-reactive protein(hs-CRP) with sudden cardiac death of coronary artery disease.Methods Clinical data of 80 patients with coronary artery disease were collected,and according to whether occurred coronary heart sudden cardiac death,the patients were divided into the observation group(coronary heart disease with sudden cardiac death group) and the control group(coronary heart disease with non-sudden death group),each group had 40 cases.The levels of serum UA,low-density hpoprotein cholesterol (LDL-C),blood sugar,hs-CRP of the two groups were detected and compared.Results The UA and hs-CRP levels of male and female in the observation group were (444.06 ±36.44.) μmol/L,(7.29 ± 0.57) mg/L,(399.25 ± 9.91) μmol/L,(6.56 ± 0.38) mg/L,respectively,which were significantly higher than those in the control group [(289.40 ± 25.78) μmol/L,(1.04 ± 0.11) mg/L,(209.90 ±29.87) μmol/L,(1.22 ± 0.31) mg/L] (t =-15.49,-47.71,-26.90,-47.92,all P ＜ 0.01).There were no statistically significant differences in the levels of LDL-C and blood glucose between the same sex of the two groups(t =-1.34,-1.54,-1.06,-1.33,all P ＞ 0.05).Conclusion The increased levels of serum UA and hs-CRP may be associate with sudden cardiac death of coronary artery disease.
