Observation on the effect of amlodipine combined with atorvastatin calcium in the treatment of hypertension patients complicated with coronary heart disease
10.3760/cma.j.issn.1008-6706.2013.10.034
- VernacularTitle:氨氯地平联合阿托伐他汀钙治疗高血压并冠心病疗效观察
- Author:
Xiping YUE
- Publication Type:Journal Article
- Keywords:
Hypertension;
Coronary disease;
Amlodipine;
Atorvastatin calcium;
Drug therapy,combination
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(10):1515-1516
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of amlodipine combined with atorvastatin in treatment of hypertensive patients complicated with coronary heart disease.Methods 80 hypertension patients complicated with coronary heart disease were randomly divided into the observation group 40 cases,control group 40 cases.Control group was given amlodipine treatment,the observation group was given amlodipine and atorvastatin calcium therapy.The clinical efficacy of two groups were compared.Results The hypertension excellent and good rate of the observation group was 95.0％,77.5％ in the control group.The excellent and good rate of coronary heart disease in the observation group was 87.5％,75.0％ in control group.The excellent and good rate of hypertension and coronary heart disease between two groups had statistically significant differences(x2 =23.12,18.98,all P ＜ 0.05).The incidence rate of adverse reaction in observation group was 10％,control group 10％,which showed no significant difference between the two groups (P ＞ 0.05).Conclusion Amlodipine combined with atorvastatin calcium has the exact clinical efficacy in the treatment of hypertension and coronary heart disease,it can improve the patients' quality of life and worthy of clinical application.
