Observation on the effect of plasmin combined with aspirin in the treatment of acute cerebral infarction

VernacularTitle:纤溶酶联合阿司匹林治疗急性脑梗死的疗效观察
Author: Xiao LYU
Publication Type:Journal Article
Keywords: Acute cerebral infarctions; Plasmin; Aspirin; Blood rheology
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(10):1502-1503
CountryChina
Language:Chinese
Abstract: Objective To observe the clinical effect of plasmin combined with aspirin in treating acute cerebral infarction and to explore the influence to blood rheology and nerve function.Methods 148 cases with acute cerebral infarction were randomly divided into two groups.The control group (n =74) was treated by honghua injection.The study group (n =74) was treated by plasmin combined with aspirin.After treatment,the clinical effect,blood rheology and neurological recovery were observed.Results The total effective rate of the study group was 97.2％,which was significantly higher than that of the control group(74.3％) (x2 =15.88,P ＜ 0.05).The blood rheology indexes of the two groups had improved and neural function of the two groups was restored,but those in the study group were obviously better than control group (t =3.56,3.42,4.26,3.22,4.16,all P ＜ 0.05).Conclusion Plasmin combined with aspirin in treating acute cerebral infarction has accurate clinical curative effect,can markedly improve the blood rheology and promote nerve functional recovery,is worth of clinical spreading.