Clinical value of detection of ankle-brachial index combined with hs-CRP for evaluation coronary artery lesions in diabetic patients
10.3760/cma.j.issn.1008-6706.2013.11.013
- VernacularTitle:踝臂指数联合超敏C反应蛋白检测评价糖尿病患者冠状动脉病变的临床研究
- Author:
Wenhui DU
- Publication Type:Journal Article
- Keywords:
Diabetes;
Coronary artery;
C-reactive protein
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(11):1628-1630
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of the detection of ankle-brachial index(ABI) combined with high-sensitivity C-reactive protein (hs-CRP) for evaluation coronary artery lesions in diabetic patients.Methods According to the diagnostic results of 256 layer speed CT,238 diabetic patients were divided into the group without coronary artery lesions(52 cases),the group with mild coronary artery lesions(103 cases) and the group with severe coronary artery lesions (83 cases).The ABI and hs-CRP were detected.The relationship between ABI,hs-CRP and cartotid artery intima-media thickness(IMT) were analyzed.Results The ABI and hs-CRP of the group with mild coronary artery lesions or with severe coronary artery lesions were lower than that of the group without coronary artery lesions(P ＜0.05 or P ＜0.01).The ABI and hs-CRP of the group with mild coronary artery lesions were lower than that of the group with severe coronary artery lesions(all P ＜ 0.05).The IMT was (1.37 ± 0.29) mm in the group with coronary artery lesions,which had a negative correlation with A BI (r =-0.2195,P ＜ 0.05) and a positive correlation with hs-CRP(r =0.3946,P ＜ 0.05).Conclusion The detection of ABI combined with hs-CRP can be used to evaluate diabetic patients with coronary artery disease.
