Clinical signicance of the detection of plasma N-teminal pro brain natriuretic peptid (NT-pro-BNP) level in the patients with different heart failure
10.3760/cma.j.issn.1008-6706.2013.09.029
- VernacularTitle:心功能不全患者血浆B型脑钠肽前体N端片段水平检测的临床意义
- Author:
Chunyun ZHANG
;
Lu SHEN
;
Zhangsheng LI
- Publication Type:Journal Article
- Keywords:
Cardiac Oulput,low;
Peptide Hormones
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(9):1343-1344
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical significance of plasma N-teminal pro brain natriuretic peptide (NT-pro-BNP) level in diagnosis and evaluation prognosis of patients with different heart failure.Methods Plasma NT-pro-BNP level was detected and compared in all patients at the first day and a week after the patients' condition turn better.Results The level of plasma NT-pro-BNP for the high blood pressure's heart disease and the chronic heart failure of coronary heart disease and the chronic heart failure of cor pulmonale were significantly higher than normal (t =2.98,t =2.98,t =2.98,P ＜ 0.01).The level of plasma NT-pro-BNP was reduced after treatment (t =2.56,t =2.75,t =2.88,P ＜ 0.05,P ＜ 0.01,P ＜ 0.01).The level of plasma NT-pro-BNP was gradually increased by the increased degree of the heart failure(t =2.78,P ＜ 0.05).Conclusion The levels of plasma NT-pro-BNP at acute stage for the high blood pressure's heart disease and the chronic heart failure of coronary heart disease and the chronic heart failure of cor pulmonale were increased obviously and descend by the patients' condition return.The level of plasma NT-pro-BNP can monitor patients' condition and estimate the heart failure patients' prognosis.
