Forms and molecular mechanisms of cell death after cerebral ischemia
10.3760/cma.j.issn.1673-4165.2013.04.011
- VernacularTitle:脑缺血后细胞死亡的形式及其分子机制
- Author:
Zhanbo WANG
;
Hui DANG
;
Yi ZHU
- Publication Type:Journal Article
- Keywords:
Brain Ischemia;
Necrosis;
Apoptosis;
Autophagy;
Neurons
- From:
International Journal of Cerebrovascular Diseases
2013;(4):310-315
- CountryChina
- Language:Chinese
-
Abstract:
Death of nerve cells after cerebral ischemia have a variety of forms,including cell necrosis occurs immediately in ischemic core area and the subsequent apoptosis and autophagy induced by oxidative stress and inflammatory response in the course of reperfusion.After cerebral ischemia,a variety of different molecular mechanisms eventually lead to cell death,and the process involves several signaling pathways.Intervention of different forms and mechanisms of cell death may alleviate cell death after cerebral ischemia.
