Pathogenesis of cerebra small vessel diseases
10.3760/cma.j.issn.1673-4165.2013.04.008
- VernacularTitle:脑小血管病的发病机制
- Author:
Jie TANG
;
Jianhui FU
- Publication Type:Journal Article
- Keywords:
Cerebral Small Vessel Diseases;
Endothelium,Vascular;
Blood-Brain Barrier;
Brain Ischemia;
Cerebrovascular Circulation;
Cerebral Amyloid Angiopathy;
Mutation
- From:
International Journal of Cerebrovascular Diseases
2013;(4):293-298
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral small vessel diseases refer to small intracranial vascular lesions caused ischemic or hemorrhagic disease.Although researches have performed a large number of studies for its pathogenesis,it remains unclear now.This article reviews the pathogenesis of cerebral small vessel diseases from endothelial dysfunction,blood-brain barrier damage,ischemic and hypoperfusion,amyloid deposition,and genetic factor.