Progression of microRNA in gastric cancer
10.3760/cma.j.issn.1673-422X.2013.05.013
- VernacularTitle:胃癌中微小RNA相关研究进展
- Author:
Jing HAN
;
Zhiqiang LING
- Publication Type:Journal Article
- Keywords:
Gastric neoplasms;
MicroRNAs
- From:
Journal of International Oncology
2013;(5):359-362
- CountryChina
- Language:Chinese
-
Abstract:
Recently,many studies find that microRNA plays a key role in the development,diagnosis,treatment and prevention of gastric cancer.It is confirmed that miR-451 can be used as a useful biomarker for the screening of gastric cancer.Studies also show that miR-203 and miR-21 may become diagnostic markers of gastric cancer.MicroRNA can play the role of oncogenes,and also can play the role of tumor suppressor gene,such as miR-141 plays the role of tumor suppressor gene through inhibition of the positive fibroblast growth factor receptor 2 gene expression.
