Mutual regulation of microRNA and DNA methylation in cancer
10.3760/cma.j.issn.1673-422X.2013.05.003
- VernacularTitle:微小RNA与DNA甲基化相互调控在肿瘤中的作用
- Author:
Qianqian DONG
;
Xiaofeng LIU
;
Ruilian SHANG
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
DNA methylation;
Neoplasms
- From:
Journal of International Oncology
2013;(5):329-331
- CountryChina
- Language:Chinese
-
Abstract:
Both microRNA and DNA methylation are the important contents of epigenetic modification.Lots of studies have confirmed that mutual regulation of microRNA and DNA methylation involve in tumorgenesis and development of cancer.The studies of their mechanisms bring some new ideas for investigating the pathogenesis of tumors,and provide a theoretical basis for the early diagnosis and treatment.