Research development of H-1 parvovirus application in cancer therapeutics
10.3760/cma.j.issn.1006-9801.2013.04.023
- VernacularTitle:细小病毒H-1抗肿瘤作用的研究进展
- Author:
Hui SHI
- Publication Type:Journal Article
- Keywords:
H-1 parvovirus;
Glioblastoma;
Burkitt lymphoma;
Liver neoplasms;
Pancreatic ductal adenocarcinoma;
Viral nonstructural protein 1
- From:
Cancer Research and Clinic
2013;(4):281-284
- CountryChina
- Language:Chinese
-
Abstract:
Since there is no specific symptoms after human have been infected by parvovirus,parvovirus was administered as a potential cancer therapeutics.Parvovirus was employed as an effective treatment in glioblastoma multiforme,Burkitt' s lymphoma,liver cancer,pancreatic carcinoma,breast cancer and colon cancer.Anti-tumor effects of parvovirus were approved to be associated with its oncolytic effects,non-structural protein 1 and immunoregulation.