Progress of dendritic spines in the nervous system diseases
10.3760/cma.j.issn.1673-4408.2013.03.021
- VernacularTitle:树突棘在神经系统疾病中的研究进展
- Author:
Ying WANG
- Publication Type:Journal Article
- Keywords:
Dendritic spines;
Plasticity;
Learning and memory;
Aging
- From:
International Journal of Pediatrics
2013;(3):287-289
- CountryChina
- Language:Chinese
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Abstract:
Dendritic spines are functional protrusions on neuron dendrites and formation of excitatory synaptic sites.Dendritic spines contain a variety of cell surface receptors,actin cytoskeleton,scaffolding proteins and other components,which regulate the growth of dendritic spines maturation and structure.Multiple components within dendritic spines not only have effects on expression of its shape and structure,but also on the function.Morphology of dendritic spines is closely related with its function.Its shape is affected by many factors in the changing process.So dendritic spine plasticity is an important aspect of synaptic function in the central nervous system,and is closely related with learning and memory function and central nervous system diseases.
