Prevention and treatment of rotavirus infections in children
10.3760/cma.j.issn.1673-4408.2013.03.014
- VernacularTitle:婴幼儿轮状病毒感染的防治进展
- Author:
Rui ZHOU
- Publication Type:Journal Article
- Keywords:
Rotavirus;
Prevention;
Treatment;
Diarrhea
- From:
International Journal of Pediatrics
2013;(3):261-263
- CountryChina
- Language:Chinese
-
Abstract:
Rotavirus(RV) is the leading pathogen of acute gastroenteritis in children,accounting for approximately 5 ％ of deaths worldwide.By now,no specific antiviral treatment is available for rotavirus infection.The duration of passive immunization is shorter than active,so oral immunoglobulin for prevention and treatment of rotavirus might not be the best strategy.Currently,two rotavirus vaccines-Rotarix and RotaTeq are licensed and used in many countries,and they have been recognized as powerful weapons to combat deaths from acute gastroenteritis.The trials of interventions,such as oral rehydration,zinc preparations,probiotics and nitazoxanide are testified to be effective for some young children with acute gastroenteritis.This paper reviews the progress of prevention and treatment of rotavirus infections in children.
