Ultrastructural localization of 28 kDa glutathione S-transferase in adult Clonorchis sinensis.
10.3347/kjp.2002.40.4.173
- Author:
Sung Jong HONG
;
Jae Ran YU
;
Shin Yong KANG
- Publication Type:Original article ; Research Support, Non-U.S. Gov't
- Keywords:
Clonorchis sinensis;
Glutathione S-transferase;
immunoelectron microscopy
- MeSH:
Animals;
Clonorchis sinensis/*enzymology;
Glutathione Transferase/*metabolism/physiology;
Immunohistochemistry;
Microscopy, Immunoelectron;
Molecular Weight;
Support, Non-U.S. Gov't
- From:The Korean Journal of Parasitology
2002;40(4):173-176
- CountryRepublic of Korea
- Language:English
-
Abstract:
Glutathione S-transferase (28GST) with molecular mass of 28 kDa is an antioxidant enzyme abundant in Clonorchis sinensis. In adult C. sinensis, 28GST was localized in tegumental syncytium, cytons, parenchyma, and sperm tails examined by immunoelectron microscopy. C. sinensis 28GST was earlier found to neutralize bioreactive compounds and to be rich in eggs. Accordingly, it is suggested that 28GST plays important roles in phase II defense system and physiological roles in worm fecundity of C. sinensis.
