Advances in diagnosis and treatment of Takayasu arteritis in children
10.3760/cma.j.issn.1673-4408.2013.03.024
- VernacularTitle:儿童大动脉炎的诊断和治疗进展
- Author:
Hongmei SONG
;
Yue ZHANG
- Publication Type:Journal Article
- Keywords:
Takayasu arteritis;
Children;
Diagnosis;
Treatment
- From:
International Journal of Pediatrics
2013;(3):297-300
- CountryChina
- Language:Chinese
-
Abstract:
Takayasu arteritis (TA) is a devastating vasculitis of the aorta and its major branches,coronary and pulmonary arteries.The clinical manifestations in children are less specific than in adnlts:the disease in children presents with fever,arthralgias,vomiting,weight loss and hypertension.Conventional angiography,which is recognized as the golden standard in evaluating vascular lesions in TA,combined with computer tomography angiography (CTA),magnetic resonance angiography (MRA),ultrasonography,could not only provide important information for early diagnosis,but also detect disease activity.New immunosuppressive agents and biological therapies,such as TNF-a blocking agents,have been verified to be effective although corticosteroids and conventional immunosuppressive agents are still basic treatment.
