Research Progress for Detection Techniques of Mycotoxins Biomarkers In Vivo
10.11842/wst.2013.03.035
- VernacularTitle:体内真菌毒素生物标记物检测方法的研究进展＊
- Author:
Liwei XIE
;
Weijun KONG
;
Meihua YANG
;
Zhen OUYANG
- Publication Type:Journal Article
- Keywords:
Mycotoxins biomarkers;
in vivo;
detection techniques
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2013;(3):543-550
- CountryChina
- Language:Chinese
-
Abstract:
Mycotoxins are secondary metabolites produced by certain genera of toxigenic fungus and frequently oc-cur in food worldwide. Humans and animals can be simultaneously exposed to different mycotoxins through the diet. As most mycotoxins are highly toxic, carcinogenic, teratogenic and mutagenic, they have posed grave health threats to consumers. Determination of mycotoxins and their main metabolites in blood, urine, bile, milk or faeces can serve as biomarkers and can facilitate effective exposure assessment, crucial to estimate mycotoxin related dis-ease risk. According to reason mentioned above, the study of metabolism and evaluations of mycotoxins in biologi-cal fluids have been paid increasing attention since the results may offer valuable indications on the real risk for consumers. Therefore, it is important to develop proper analytical methods for the rapid quantitative and qualita-tive measurement of mycotoxins and key metabolites in vivo. This paper reviewed some biomarkers and their harm to animals and humans, systematically summarized the research progress of analytical methods and prospected the development trends.
