Research on the Relationship between the Deferment of the Promotion of MRI Manifestation by Gd-BOPTA of HCC and Expression of PCNA,PTEN
10.3969/j.issn.1005-5185.2009.06.012
- VernacularTitle:Gd-BOPTA延迟增强扫描MRI表现与原发性肝癌PCNA、PTEN表达相关性研究
- Author:
Jian LU
;
Tao ZHANG
;
Weiju CAO
;
Bin CHENG
;
Ding DING
;
Jifeng JIANG
;
Chunyan GU
;
Xuefei YANG
- Publication Type:Journal Article
- Keywords:
liver cancer;
Gd-BOPTA;
MRJ;
PCNA;
PTEN
- From:
Chinese Journal of Medical Imaging
2009;(6):438-441
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To discuss the function of Gd-BOPTA on the deferment of manifestation of MRI,which bring influence to the immune mensuration of antigen PCNA,PTEN.Materials and Methods:Scanning with MRI on the 35 patients with pathologically verified HCC the image were analyzed concretely.Pathologic diagnose was made with Edmondson pathologic classification standard,and it was expressed with index of PCNA and PTEN of immune quantitative analysis.Results: HCC was negatively related to the index of PCNA,and most patients with high index were lightly or not deferred enhanced(13/16),Patients with low index were evidently enhanced ( 10/19).The degree of HCC deferred enhancing was positively related to the expression of PTEN.Most HCCs( 15/17) with negative PTEN were lightly or not deferred enhanced,while positive patients of PTEN were mostly enhanced obviously(11/18).Conclusion: Deferment of Gd-BOPTA can be used to basically estimate the tincture of tumor biology,therefore,the enhanced degree of which,the PCNA,PTEN,can offer great help in choosing the therapuetic method and estimating the outcome of the the therapy.
