Clinical characteristics and prognostic factors of primary signet-ring cell adenocarcinoma of the lung: a report of 22 cases
10.3781/j.issn.1000-7431.2009.07.018
- VernacularTitle:肺原发性印戒细胞癌22例临床特征和预后因素分析
- Author:
Hui NING
;
Yi XIE
;
Chengzhi WANG
;
Wanpeng WU
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Carcinoma,signet ring cell;
Survival analysis;
Prognosis
- From:
Tumor
2009;(7):684-686
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical characteristics and prognostic factors of primary signet-ring cell adenocarcinoma of lung. Methods:The clinical features of 22 patients with primary signet-ring cell adenocarcinoma of lung from the year 1981 to 2007 were analyzed retrospectively and made a statistical analysis on the prognostic factors. Results:Postoperative pathologic examination was an important method to confirm the primary signet-ring cell adenocarcinoma of lung and surgery was the main therapeutic approach. The 1-, 3-, and 5-year survival rates were 63.0%, 53.3%, and 37.7%, respectively. Statistical analysis indicated that smoking, tumor size, complete resection, and tumor staging were the independent prognostic factors for patients with primary signet-ring adenocarcinoma of lung.Conclusion:The primary signet-ring cell adenocarcinoma of lung has higher malignancy. Invasion and migration frequently occur. Its prognosis is poor.
