Studies on Qualitative and Quantitative Methods of Shenbai Concentrated Pills

VernacularTitle:参白浓缩丸质量标准研究
Author: Xiaowei DU ; Wenwei ZHANG ; Dan YU ; Hongxin CAO ; Yan LIU ; Peican WU
Publication Type:Journal Article
Keywords: Shenbai concentrated pills; quality standards; TLC; HPLC
From: Chinese Journal of Experimental Traditional Medical Formulae 2009;(7):19-22
CountryChina
Language:Chinese
Abstract: Objective:To study the qualitative and quantitative methods of Shenbai concentrated pills. Methods:Danshen root and lightyellow sophora root in Shenbai concentrated pills were identified with the method of TLC. The contents of astragaloside Ⅳ and paeoniflorin were determined with the method of HPLC. Results: For TLC, the spots of the two herbal drugs were well separated and without interference. Quantitative analysis of HPLC showed that the average recovery of astragaloside 1V was 100.82% (RSD1.73%) with the RSD values of precision, repeatability and stability tests were 2.79%, 1.48% and 1.44%, respectively; and the average recovery of paeoniflorin was 99.83% (RSD2.34%) with the RSD values of precision, repeataibility and stability tests were 2.25%, 2.16% and 1.60%, respectively. Conclusions: The methods set up by this study are accurate and easy to perform with the merits of good resolution, specificity and reproducibility. It could effectively control the quality of Shenbai concentrated pills.