Influence of different process conditions on insoluble particles in Chinese medicine injection
10.3760/cma.j.issn.1673-4246.2013.07.013
- VernacularTitle:不同工艺条件对中药注射剂不溶性微粒的影响
- Author:
Zhiqiang MA
;
Binli LIU
;
Lu LIU
;
Chengke CAI
;
Jian NI
- Publication Type:Journal Article
- Keywords:
Chinese medicine injection;
Insoluble particles;
Influence factor
- From:
International Journal of Traditional Chinese Medicine
2013;(7):616-618
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the influence of usual processing steps on insoluble particles in Chinese medicine injection,with Shuanghuanglian injection as an example.Methods Light block method was adopted to analyze the influence of the different conditions of sterilization,ultra filtration and PH value on insoluble particles in Chinese medicine injection.Results Sterilization,ultra filtration and PH value caused the change of insoluble particles in Chinese medicine injection.Conclusion The comprehensive use of sterilization,ultra filtration,PH value can reduce the quantity of insoluble particles and clinical risk.
