Clinical features of pneumonia in children with elevated alanine aminotransferase
10.3969/j.issn.1000-3606.2013.07.009
- VernacularTitle:肺炎伴血清丙氨酸转氨酶升高患儿的临床特征分析
- Author:
Min LU
;
Wei JI
;
Feng HUANG
;
Ying CHEN
;
Yongdong YAN
;
Lanping GAO
- Publication Type:Journal Article
- Keywords:
pneumonia;
alanine aminotransferase;
child
- From:
Journal of Clinical Pediatrics
2013;(7):626-628
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To investigate the clinical features of pneumonia in children with elevated alanine aminotransferase(ALT). Methods Clinical and laboratory data of 3 979 children with pneumonia admitted to the hospital were collected and retrospectively analysed, and ALT was detected in all cases. Results In 3 979 children with pneumo-nia, elevated ALT (13.78%) was found in 548 cases, most of which had mildly elevated ALT and were infants less than 6 months. The average age in elevated ALT group was less than that in normal ALT group (P=0.000). Apart from the symp-toms of pneumonia, most of them had non-specific clinical symptoms, 169 cases (30.84%) with anorexia or feeding dif-ficulties. 22 cases (4.01%) with poor spirit or weak, 10 cases (1.82%) with crying or abdominal pain;6 cases (1.09%) with dark urine; 4 cases (0.73%) with skin and/or sclera jaundice, 2 cases (0.36%) with bleeding tendency. Children in mildly elevated ALT group recovered faster than in moderate-to-severe elevated ALT group. Conclusions Mildly elevated ALT was most common in pneumonia with elevated ALT which was more likely to occur in younger age group. Clinical mani-festations were often non-specific with good outcomes.
