Clinical Analysis of Serum Theophylline Level above Normal Th erapeutical Range in 32 cases
10.3870/j.issn.1004-0781.2001.04.042
- VernacularTitle:茶碱血药浓度超出正常范围32例临床分析
- Author:
Qili BI
;
Qikun ZHENG
;
Yueling NI
- Publication Type:Journal Article
- From:
Herald of Medicine
2001;(4):252-253
- CountryChina
- Language:Chinese
-
Abstract:
Clinical symptoms with serum theoph ylline level above normal therapeutical range were analysed in 32 case. Methods: Theophylline 20μgmL-1 invserum was defined as the upper limit of normal therapeutical range. The case records with serum theo phylline concentraed ≥20μgmL-1 were selected from 324 cases, analyse d in combination with clinical symptoms. Results: Patients with serum theophylline concentration ≥20 μgmL-1 showed toxic reacti ons involving cardiovasucular, digestive, and nervous systems. One third of them took simultaneously other drugs which could decrease the metabolism of theophyl line. Conclusion: In order to prevent and diagnose toxicr eactions effectively, it's necessary to monitor the patients'serum theophylline level.
