Treating acute myocardial infarct with recombinant tissue-type plasminogen activator
10.3870/j.issn.1004-0781.2001.03.003
- VernacularTitle:重组组织型纤溶酶原激活药治疗急性心肌梗死
- Author:
Zhongdu GAO
;
Li LIU
;
Heng JIANG
;
Baohong LIU
;
Benxiang CAI
- Publication Type:Journal Article
- From:
Herald of Medicine
2001;(3):150-151
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To Observe the effect of recombinant tissue-type plasminogen activator (rt-PA) in treatment of acute myocardial infarct.Methods:Two groups of patients were observed.The subjects in the control group (35 patients) were treated with routine intervention,while those in thrombolysis group (15 patients) were treated with rt-PA in addition to the routine intervention.Results:There is a better outcome in the thrombolysis group as compared with that in the control group,in terms of length of angina relief,degree and length of EKG changes as well as the time for serum enzyme changes.The mortality rate in the thrombolysis group was significantly lower than that in the control group (P＜0.01).Conclusion:The rt-PA for thrombolysis in acute myocardial infarct patients can reduce the infarct size and improve the cardiac function rapidly as well as increase the survival rate.
